Weight management

Intervention2 papers1 finding

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

1 lab in 1 country

Funders: National Natural Science Foundation of China and 5 more

  • Humans1

Associations

1

Brain age acceleration

downin humans1−30%

1 study
  1. Weight management lowers the risk of brain age acceleration in humans (-30%).

    Humans16-yearmalesn = 16,484

    Joint Effects of Long-Term Obesity and Genetic Susceptibility on Sex-Specific Brain Aging · Obesity (Silver Spring, Md.) · 6 Sep 2026

Brain age acceleration →

Funding

Innovative UK£8mNational Institute of Child Health and Human DevelopmentUS$785.4kNational Heart, Lung, and Blood InstituteUS$778.2k5 grants since 2023

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