Vigorous activity

Exposure

3 papers4 findings

  • 2 independent labs in 2 countries
  • 1 finding against
  • Humans2

Outcomes

1

Subjective well-being

no changein humans1upin humans1

1 study
  1. Vigorous activity has no effect on subjective well-being in humans (β -0.09 (-0.22, 0.05)).

    “no significant association for ≥1 h/day (-0.09 [-0.22, 0.05])”

    Humansfrail older adults≥1 h/day vs no activity

    Intensity-Specific Physical Activity and Subjective Well-Being in Older Adults With and Without Frailty

    GSA 2025 abstract31 Dec 2025

  2. Vigorous activity improves subjective well-being in humans (β 0.17 (0.11–0.23)).

    “0.17 (0.11–0.23) for ≥1 h/day of vigorous activity (reference: no activity)”

    Humansnon-frail older adults≥1 h/day vs no activity

    Intensity-Specific Physical Activity and Subjective Well-Being in Older Adults With and Without Frailty

    GSA 2025 abstract31 Dec 2025

Associations

2

Mortality

downin humans1

1 study
  1. Vigorous activity lowers the risk of mortality in humans (lowest risk).

    “3-5 sessions per week generating 1-2.4 h of vigorous activity is associated with the lowest all-cause mortality risk”

    Review1-2.4 h per week

    The Oxygen Imperative: Cardiorespiratory Fitness, Dose-Dependent Exercise Thresholds, and Longevity-A Narrative Review

    Journal of clinical medicine13 Jun 2026

Pressure-independent arterial stiffness index

downin humans1

1 study
  1. Vigorous activity is associated with pressure-independent arterial stiffness index in humans (β ≈-0.12; p < .001).

    “In intensity-specific models, vigorous activity was consistently associated with lower ASI-PI (β ≈-0.12; p < .001)”

    Humansmultivariable adjustedn = 34,105

    Intensity matters: vigorous activity is associated with lower pressure-independent arterial stiffness in the UK Biobank

    The journals of gerontology. Series A, Biological sciences and medical sciences28 Apr 2026

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