Urinary tract infection
Urinary tract infection has been studied in 7 papers since 2019: 6 observational studies in people, 1 in animals; 2 in the past year. The newest paper, Jun 17, 2026: “A multistate model of frailty progression after severe infections in adults ≥65 years in England: a matched-cohort study”.
7 papers study it3 findingsUpdated
“Our results showed that all three exposures were associated with an elevated risk of dementia, especially in the first year after exposure diagnosis.”
None of its findings points the other way.
- 3 independent labs in 2 countries
- Funders: Deutsche Forschungsgemeinschaft and 7 more
- Humans6
- Animals1
What did studies of urinary tract infection find?
1Studies of urinary tract infection measured 1 outcome; the most studied are bladder tertiary lymphoid tissue (1 study).
Bladder tertiary lymphoid tissue
no changein mice1
1 study
Bladder tertiary lymphoid tissue
no changein mice1
Urinary tract infection showed no clear effect on bladder tertiary lymphoid tissue in mice (experimental UTI).
“bTLT formation was dependent on aging and independent of infection.”
Animalsexperimental UTIbladderfemales
Tertiary lymphoid tissue develops during normal aging in mice and humans
bioRxiv (Cold Spring Harbor Laboratory)Preprint
What is urinary tract infection linked with?
1Studies link urinary tract infection with 1 measure, most often dementia (2 studies).
Dementia
upin humans2OR 1.23
2 studies
Dementia
upin humans2OR 1.23
Urinary tract infection is linked with a higher risk of dementia in the first year after exposure diagnosis.
“Our results showed that all three exposures were associated with an elevated risk of dementia, especially in the first year after exposure diagnosis.”
Humansin the first year after exposure diagnosis0–1 year after exposure
GSA 2024 abstract
Urinary tract infection is linked with a higher risk of dementia in humans (OR 1.23 (95% CI: 1.16-1.30)).
“Influenza, urinary tract infections, intestinal infections, and sepsis showed independent positive associations with subsequent dementia diagnosis, irrespective of other comorbidities”
Humansn = 58,208
The journal of prevention of Alzheimer's disease