Umbilical cord pluripotent-like stem cells

1. Umbilical cord pluripotent-like stem cells increase thymic epithelial cell activity in M. monkeys cells.

   “and increased the activity of ageing TECs.”

   Cellsageing TECsthymic epithelial cell48 hours

   Umbilical cord subtotipotent-like stem cells reverse the ageing of thymic epithelial cells by inducing reprogramming of the whole-genome methylation and transcription profile

   Research Square·15 Dec 2022Preprint

1. Umbilical cord pluripotent-like stem cells decrease cellular senescence in M. monkeys cells.

   “Coculture of ageing TECs with UCSSCs for 48 hours significantly reduced the expression levels of ageing markers such as P16, P21 and p53”

   Cellsageing TECsthymic epithelial cell48 hours

   Umbilical cord subtotipotent-like stem cells reverse the ageing of thymic epithelial cells by inducing reprogramming of the whole-genome methylation and transcription profile

   Research Square·15 Dec 2022Preprint

More on Cellular senescence

1. Umbilical cord pluripotent-like stem cells increase thymus regeneration in M. monkeys.

   “UCSSCs could promote thymus regeneration in ageing macaque monkeys”

   Animalsthymus

   Umbilical cord subtotipotent-like stem cells reverse the ageing of thymic epithelial cells by inducing reprogramming of the whole-genome methylation and transcription profile

   Research Square·15 Dec 2022Preprint