Tyramine

  • 1 lab in 1 country
  • Funders: Biotechnology and Biological Sciences Research Council and 3 more
  • Model organisms1

Outcomes

1

Lifespan

upin flies1

1 study
  1. Tyramine extends lifespan in flies.

    “Increased neuronal synthesis of TA boosts health and longevity in both sexes”

    Model organisms

    ß-adrenergic-like signalling engages CrebB in Drosophila gut to promote female longevity

    Nature communications2 Apr 2026

Latest

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bioRxiv

Restoring Tyr1R signaling aids motor function in flies

Overexpressing the receptor in adrenergic-like neurons prolonged lifespan, restored calcium signaling, and improved locomotor performance in aged fruit flies.Overexpressing the receptor in adrenergic-like neurons prolonged lifespan, restored calcium signaling, and improved locomotor performance in aged fruit flies.

Preprint: experiments in fliesInterventions