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Trilocked photodynamic senolytic inducer

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Outcomes

2

Cellular senescence

downin cells1

1 study

  1. Trilocked photodynamic senolytic inducer decreases cellular senescence in cells.

    “trilocked PDSI elicited senescent cell clearance predominantly via the immunogenic necroptosis pathway”

    Cells

    Trilocked Photodynamic Senolytic Inducer Potentiating Immunogenic Senescent Cell Removal for Liver Fibrosis Resolution

    Journal of the American Chemical Society30 Apr 2025

More on Cellular senescence

Liver fibrosis

downin animals1

1 study

  1. Trilocked photodynamic senolytic inducer decreases liver fibrosis.

    “enables high-contrast NIRF/PA imaging and effective liver fibrosis resolution in vivo”

    Animalsin vivoliver

    Trilocked Photodynamic Senolytic Inducer Potentiating Immunogenic Senescent Cell Removal for Liver Fibrosis Resolution

    Journal of the American Chemical Society30 Apr 2025

More on Liver fibrosis

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