Total knee replacement
4 papers1 finding
- 1 lab
- Funder: National Institute on Aging
- Humans3
Upstream
1Semaglutide
downin humans1−25% reduction
1 study
Semaglutide
downin humans1−25% reduction
Semaglutide decreases total knee replacement in humans (25% reduction).
“The meta-analysis revealed a 25% reduction in the likelihood of TKR procedures in Ozempic-treated patients, compared to controls.”
Review
ENDO 2025 abstract22 Oct 2025
Funding
2 grants since 2023National Institute on AgingUS$3.1m
Optimizing a Remote-based Physical Activity Intervention for Adults with Total Knee Replacement
National Institute on AgingUniversity of South Carolina at ColumbiaUS$579.8k2024–2029
Physical Activity and Weight Loss to Improve Function and Pain after Total Knee Replacement
National Institute on AgingUniversity of South Carolina at ColumbiaUS$476.5k2021–2027
Latest
1 in 12 monthsGSA 2025 Abstract
Understanding and Measuring Resilience: From Bench to Bedside
Study in peopleBiomarkers
ENDO 2025 Abstract
SAT-725 Impact of Ozempic (Semaglutide) on Reducing Total Knee Replacement Procedures in Patients with Osteoarthritis
Meta-analysis of studies in peopleSemaglutide
The Journals of Gerontology, Series A
Characterization of Dynamic Adaptation to Stressors Using Multisystem Stimulus-Response Data: The Study of Physical Resilience in Aging Pilot
Cohort study of 79 peopleBiomarkers
medRxiv
Multivariate Profiling of Physical Resilience in Older Adults After Total Knee Replacement Surgery
Preprint: cohort study of 112 peopleBiomarkers