TJ0113
1 paper2 findings
- 1 lab
- Cells1
Outcomes
2THBS1
downin cells1
1 study
THBS1
downin cells1
TJ0113 decreases THBS1 in cells.
“This decline directly diminishes histone H3 lysine 18 lactylation (H3K18la), consequently suppressing transcription of the pro-inflammatory gene thrombospondin-1 (THBS1)”
Cellssenescent cells
Research (Washington, D.C.)5 Nov 2025
Lactate
downin cells1
1 study
Lactate
downin cells1
TJ0113 decreases lactate in cells.
“mitophagy activator TJ0113 drives metabolic reprogramming characterized by substantially reduced lactate production in senescent nucleus pulposus (NP) cells”
Cellssenescent cells
Research (Washington, D.C.)5 Nov 2025
Development
- Companies
- PhecdaMedPhase 2sarcopenia, Parkinson's disease