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Tgf-beta-neutralizing antibody

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Medical Center, University of Rochester and 7 more
  • Animals1

Outcomes

1

Fracture healing

upin mice1

1 study

  1. Tgf-beta-neutralizing antibody improves fracture healing in mice.

    “TGF-β-neutralizing Ab prevented the inhibitory effects of aged callus SCs on CaMPCs and promoted fracture healing in aged mice”

    Animalsin aged mice with fracture

    Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice

    The Journal of clinical investigation

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