Tempo@dsh

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 3 more
  • Animals1

Outcomes

4

Cellular senescence

downin cells1

1 study
  1. Tempo@dsh decreases cellular senescence in cells.

    “reducing chondrocyte senescence”

    Cellscartilage

    A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis

    Journal of nanobiotechnology31 Oct 2025

More on Cellular senescence

mTOR signalling

downin cells1

1 study
  1. Tempo@dsh inhibits mTOR signalling in cells.

    “inhibits the NF-κB and mTOR pathways”

    Cellscartilage

    A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis

    Journal of nanobiotechnology31 Oct 2025

More on mTOR signalling

NF-κB signalling

downin cells1

1 study
  1. Tempo@dsh inhibits NF-κB signalling in cells.

    “inhibits the NF-κB and mTOR pathways”

    Cellscartilage

    A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis

    Journal of nanobiotechnology31 Oct 2025

More on NF-κB signalling

Mitochondrial damage

downin cells1

1 study
  1. Tempo@dsh decreases mitochondrial damage in cells.

    “TEMPO@DSH mitigates oxidative stress-induced mitochondrial damage in chondrocytes”

    Cellsoxidative stress-inducedcartilage

    A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis

    Journal of nanobiotechnology31 Oct 2025

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