TBG096

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funder: National Key Research and Development Program of China
  • Animals1

Outcomes

3

Dihydrotestosterone

downin mice1

1 study
  1. TBG096 decreases dihydrotestosterone in mice.

    “TBG096 also reduced DHT levels, increased keratin 15 (k15) expression and regulated growth factors like IGF-1 and epidermal growth factor (EGF)”

    Animals

    TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis

    Biochemical pharmacology29 Jan 2026

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Angiogenesis

upin mice1

1 study
  1. TBG096 increases angiogenesis in mice.

    “IGF-1R/PI3K/AKT activation increased angiogenesis in the dermal papilla to promote hair follicle proliferation and differentiation.”

    Animalsdermal papilla

    TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis

    Biochemical pharmacology29 Jan 2026

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Hair growth rate

upin mice1

1 study
  1. TBG096 increases hair growth rate in mice.

    “TBG096 facilitated the transition of hair follicles from the telogen to the anagen phase, enhancing hair growth rate in a dose-dependent manner.”

    Animals

    TBG096 stimulates hair regeneration through IGF-1R-mediated angiogenesis

    Biochemical pharmacology29 Jan 2026

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