TAT-HSP10
TAT-HSP10 has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Nov 25, 2023: “Tat-heat shock protein 10 ameliorates age-related phenotypes by facilitating neuronal plasticity and reducing age-related genes in the hippocampus”.
1 paper studies it3 findingsUpdated
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Ministry of Science and ICT, South Korea and 4 more
- Animals1
What did studies of TAT-HSP10 find?
3Studies of TAT-HSP10 measured 3 outcomes; the most studied are stem cell differentiation (1 study), cognitive function (1) and cellular senescence (1).
Stem cell differentiation
upin mice1
1 study
Stem cell differentiation
upin mice1
TAT-HSP10 increases stem cell differentiation in mice.
“Administration of Tat-HSP10 increased the number of proliferating cells and differentiated neuroblasts in the dentate gyrus of adult and aged mice compared to controls”
Animalsdentate gyrus0.5 or 2.0 mg/kg3 months
Aging
Cognitive function
upin mice1
1 study
Cognitive function
upin mice1
TAT-HSP10 improves cognitive function in mice.
“Treatment with Tat-HSP10 significantly improved exploratory preferences, the number of object contacts, and the time spent swimming in the target quadrant in aged mice”
Animals0.5 or 2.0 mg/kg3 months
Aging
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
TAT-HSP10 decreases cellular senescence in mice.
“treatment with Tat-HSP10 significantly decreased P16 expression in the hippocampus of aged mice.”
Animalshippocampus0.5 or 2.0 mg/kg3 months
Aging