Tanshinone iia loaded chitosan nanoparticles

Tanshinone iia loaded chitosan nanoparticles has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Oct 3, 2022: “Tanshinone IIA loaded chitosan nanoparticles decrease toxicity of β-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease”.

Intervention

1 paper studies it3 findingsUpdated

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Model organisms1

What did studies of Tanshinone iia loaded chitosan nanoparticles find?

3

Studies of Tanshinone iia loaded chitosan nanoparticles measured 3 outcomes; the most studied are amyloid-beta deposition (1 study), paralysis (1) and lifespan (1).

Amyloid-beta deposition

downin worms1

1 study
  1. Tanshinone iia loaded chitosan nanoparticles decrease amyloid-beta deposition in worms.

    “reducing paralysis and the Aβ deposition by inhibiting the oxidative stress”

    Model organismsin CL2006 Alzheimer's disease transgenic model

    Tanshinone IIA loaded chitosan nanoparticles decrease toxicity of β-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease

    Free radical biology & medicine

More on Amyloid-beta deposition

Paralysis

downin worms1

1 study
  1. Tanshinone iia loaded chitosan nanoparticles decrease paralysis in worms.

    “attenuate the AD-like symptoms, including reducing paralysis”

    Model organismsin CL2006 Alzheimer's disease transgenic model

    Tanshinone IIA loaded chitosan nanoparticles decrease toxicity of β-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease

    Free radical biology & medicine

Lifespan

upin worms1

1 study
  1. Tanshinone iia loaded chitosan nanoparticles extend lifespan in worms.

    “CS@Tan IIA could significantly prolong the lifespan”

    Model organismsin CL2006 Alzheimer's disease transgenic model

    Tanshinone IIA loaded chitosan nanoparticles decrease toxicity of β-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease

    Free radical biology & medicine

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