Tanshinone iia

Intervention1 paper3 findingsPubChem 164676ChEBI 108595

Animals1

Outcomes

3

NRF2–KEAP1 antioxidant response

upin mice1Very low certainty

1 study

Tanshinone iia activates NRF2–KEAP1 antioxidant response in mice.
Animalsin ovariectomized micehippocampus10 mg/kg8 weeksfemales
Tanshinone IIA Improves Depression-like Behaviors in Ovariectomized Mice · CNS & neurological disorders drug targets · 6 Aug 2026

NRF2–KEAP1 antioxidant response →

Ferroptosis

downin mice1Very low certainty

1 study

Tanshinone iia inhibits ferroptosis in mice.
Animalsin ovariectomized micehippocampus10 mg/kg8 weeksfemales
Tanshinone IIA Improves Depression-like Behaviors in Ovariectomized Mice · CNS & neurological disorders drug targets · 6 Aug 2026

Ferroptosis →

Depression-like behaviors

upin mice1Very low certainty

1 study

Tanshinone iia improves depression-like behaviors in mice.
Animalsin ovariectomized micehippocampus10 mg/kg8 weeksfemales
Tanshinone IIA Improves Depression-like Behaviors in Ovariectomized Mice · CNS & neurological disorders drug targets · 6 Aug 2026

Latest

1

CNS & Neurological Disorders Drug TargetsAnimals24 Aug

Tanshinone IIA Improves Depression-like Behaviors in Ovariectomized Mice