Supersulfide donor

1 paper2 findings

1 lab in 1 country

Funders: Japan Agency for Medical Research and Development and 3 more

Animals1

Outcomes

2

Mitochondrial function

upin mouse cells1

1 study

Supersulfide donor improves mitochondrial function in mouse cells.
“similarly improved mitochondrial function exclusively in wild-type mouse embryonic fibroblasts, with no benefit observed in SQR-mutant counterparts.”
CellsWild-type cells; no benefit in SQR-mutant cellsembryonic fibroblast
Sulfide:quinone oxidoreductase drives mitochondrial supersulfide metabolism to regulate bioenergetics and longevity in eukaryotes
bioRxiv : the preprint server for biology7 Apr 2026Preprint

Lifespan

upin fission yeast cells1

1 study

Supersulfide donor extends lifespan in fission yeast cells.
“supersulfide donor supplementation selectively conferred lifespan extension in wild-type yeast, but not in SQR-deficient strain”
CellsWild-type yeast; no extension in SQR-deficient yeast
Sulfide:quinone oxidoreductase drives mitochondrial supersulfide metabolism to regulate bioenergetics and longevity in eukaryotes
bioRxiv : the preprint server for biology7 Apr 2026Preprint

Latest

1 in 12 months

bioRxiv17 Apr

Sulfide:quinone oxidoreductase drives mitochondrial supersulfide metabolism to regulate bioenergetics and longevity in eukaryotes

Preprint: experiments in miceOxidative phosphorylation