Stemjel
1 paper3 findings
- 1 lab in 1 country
- Funders: Genentech and 8 more
- Animals1
Outcomes
3Osteoarthritis
downin animals1
1 study
Osteoarthritis
downin animals1
Stemjel decreases osteoarthritis.
“We provide proof of principal that StemJEL preserves the chondrocyte niche and alleviates osteoarthritis.”
Animalspost-traumatic osteoarthritic jaw and knee joints
Cell stem cellSep 7, 2023
Joint function
upin animals1
1 study
Joint function
upin animals1
Stemjel improves joint function.
“Local delivery of StemJEL to post-traumatic osteoarthritic jaw and knee joints in rabbit, rat, and mini-pig models restores cartilage homeostasis, chondrocyte identity, and joint function.”
Animalspost-traumatic osteoarthritic jaw and knee jointsjoint
Cell stem cellSep 7, 2023
Cartilage homeostasis
upin animals1
1 study
Cartilage homeostasis
upin animals1
Stemjel improves cartilage homeostasis.
“Local delivery of StemJEL to post-traumatic osteoarthritic jaw and knee joints in rabbit, rat, and mini-pig models restores cartilage homeostasis, chondrocyte identity, and joint function.”
Animalspost-traumatic osteoarthritic jaw and knee jointscartilage
Cell stem cellSep 7, 2023
Latest
Cell Stem Cell
Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity
Experiments in rabbitsBones and joints