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Soybean protein

Intervention

2 papers5 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

  • 2 independent labs in 2 countries
  • 1 finding against
  • Animals2

Outcomes

4

Lifespan

upin mice1no changein rats1

2 studies

  1. Soybean protein has no effect on lifespan in rats.

    “The survival times and survival rates of animals fed casein and soybean protein diets were not different (P > 0.05).”

    Animalsin sodium chloride-induced early hypertensive SHRSP ratsn = 16

    Effects of source of protein and supplementary extracted isoflavones and anthocyanins on longevity of Stroke-prone Spontaneously Hypertensive (SHRSP) rats

    The Journal of toxicological sciences1 Jun 2009

  2. Soybean protein extends lifespan in mice (+27% in males, +30% in females).

    “Similarly, in SAM-P/1 mean life-spans were 265 +/- 16 d (males) and 307 +/- 23 d (females) in the soybean diet group, 27% (males) and 30% (females) longer than in the casein diet groups (P < 0.01).”

    Animalscompared with casein diet

    Dietary soybean protein compared with casein retards senescence in the senescence accelerated mouse

    The Journal of nutrition1 Nov 1993

Contracted kidney

downin mice1

1 study

  1. Soybean protein decreases contracted kidney in mice.

    “The occurrence of contracted kidneys caused by the infiltration of amyloid A protein was suppressed in SAM-R/1 mice fed the soybean protein-containing diet (P < 0.05).”

    Animalscompared with casein dietkidney

    Dietary soybean protein compared with casein retards senescence in the senescence accelerated mouse

    The Journal of nutrition1 Nov 1993

More on Contracted kidney

Secondary amyloid deposition

downin mice1

1 study

  1. Soybean protein decreases secondary amyloid deposition in mice.

    “severe secondary amyloid deposition (amyloid A protein) in the kidneys, spleen, stomach and liver was significantly suppressed, in males only, by replacing casein with soybean protein (P < 0.01).”

    Animalscompared with casein dietmales

    Dietary soybean protein compared with casein retards senescence in the senescence accelerated mouse

    The Journal of nutrition1 Nov 1993

Senile amyloid deposition

downin mice1

1 study

  1. Soybean protein decreases senile amyloid deposition in mice.

    “The deposition of senile amyloid in SAM-P/1 mice with aging was retarded by replacing casein with soybean protein (P < 0.01).”

    Animalscompared with casein diet

    Dietary soybean protein compared with casein retards senescence in the senescence accelerated mouse

    The Journal of nutrition1 Nov 1993

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