Sodium pyruvate

Sodium pyruvate decreases oocyte death in Vertebrata cells.

“Furthermore, adding NMN, sodium pyruvate, or CD38 inhibition delayed the death of postovulatory aged oocytes.”

Cellspostovulatory aged oocytes

Diminished NAD+ levels and activation of retrotransposons promote postovulatory aged oocyte (POAO) death

Cell death discovery·Feb 28, 2024

Sodium pyruvate has no effect on food intake in flies.

“However, the intake of sodium pyruvate did not significantly affect the fecundity or food intake of female flies.”

Model organismsfemales

Diet supplementation with sodium pyruvate increases sleep time and lifespan in Drosophila model

Archives of insect biochemistry and physiology·Jan 1, 2024

Sodium pyruvate has no effect on fecundity in flies.

“However, the intake of sodium pyruvate did not significantly affect the fecundity or food intake of female flies.”

Model organismsfemales

Diet supplementation with sodium pyruvate increases sleep time and lifespan in Drosophila model

Archives of insect biochemistry and physiology·Jan 1, 2024

Sodium pyruvate increases sleep duration in flies (+53.98%).

“the group sleep duration of female flies significantly increased by 53.98% when exposed to the sodium pyruvate concentration.”

Model organisms0.2 mol/Lfemales

Diet supplementation with sodium pyruvate increases sleep time and lifespan in Drosophila model

Archives of insect biochemistry and physiology·Jan 1, 2024

Sodium pyruvate extends lifespan in flies (+8.33% median lifespan).

“0.2 mol/L of sodium pyruvate increased the median lifespan of female flies by 8.33%.”

Model organisms0.2 mol/Lfemales

Diet supplementation with sodium pyruvate increases sleep time and lifespan in Drosophila model

Archives of insect biochemistry and physiology·Jan 1, 2024