Sodium lactate

1 paper5 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Human trial1

Outcomes

NfL

downin humans1

1 study

Sodium lactate decreases NfL in humans (p < 0.001).
“reductions in plasma BD‐tau ( p <0.001), pTau217 ( p <0.001), pTau181 ( p <0.001), GFAP ( p <0.001), and NfL ( p <0.001) in both AD and CH groups after lactate infusion”
Human trialplasma120 minutes
Acute effects of lactate infusion on metabolism, AD biomarkers, and cognition; the LEAN study
AAIC 2025 abstract8 Jan 2026

Latest

1 in 12 months

AAIC 2025 Abstract8 Jan

Acute effects of lactate infusion on metabolism, AD biomarkers, and cognition; the LEAN study

Non-randomised trial in peopleInterventions

Paper

Sodium lactate

Outcomes

Latest

Acute effects of lactate infusion on metabolism, AD biomarkers, and cognition; the LEAN study

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