Small heat shock protein-derived mini-chaperones
Small heat shock protein-derived mini-chaperones has been studied in 1 paper since 2022: none in people yet, 1 review. No study of it in people or animals has been published yet. The newest paper, Dec 12, 2022: “Emerging therapeutic roles of small heat shock protein-derived mini-chaperones and their delivery strategies”.
1 paper studies it2 findingsUpdated
What did studies of Small heat shock protein-derived mini-chaperones find?
2Studies of Small heat shock protein-derived mini-chaperones measured 2 outcomes; the most studied are cellular senescence (1 study) and disease symptoms (1).
Cellular senescence
downin reviews1
1 study
Cellular senescence
downin reviews1
Small heat shock protein-derived mini-chaperones decrease cellular senescence.
“sHsp mini-chaperones have shown a wide range of therapeutic effects, such as anti-aggregation of proteins, anti-apoptotic, anti-inflammatory, anti-oxidant, senolytic, and anti-platelet activity.”
Review
Biochimie
Disease symptoms
downin reviews1
1 study
Disease symptoms
downin reviews1
Small heat shock protein-derived mini-chaperones decrease disease symptoms.
“The administration of mini-chaperones into the several disease animal models, including experimental autoimmune encephalomyelitis, cataract, age-related macular degeneration, glaucoma, and thrombosis through various routes reduced symptoms or prevented the progression of the disease.”
Reviewin disease animal models
Biochimie