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Small chemical molecules

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

3

Inflammation

downin rats1

1 study

  1. Small chemical molecules decrease inflammation in rats.

    “SCM-treated groups exhibited reduced cartilage erosion, lower inflammatory marker expression”

    Animalschemically induced OAcocktailcartilagefemales

    Experimental Confirmation of Osteoarthritis Repair In Vivo Using Epigenetic Reprogramming with Small Chemical Molecules

    bioRxiv (Cold Spring Harbor Laboratory)14 Mar 2025Preprint

More on Inflammation

Cartilage erosion

downin rats1

1 study

  1. Small chemical molecules decrease cartilage erosion in rats.

    “SCM-treated groups exhibited reduced cartilage erosion”

    Animalschemically induced OAcocktailcartilagefemales

    Experimental Confirmation of Osteoarthritis Repair In Vivo Using Epigenetic Reprogramming with Small Chemical Molecules

    bioRxiv (Cold Spring Harbor Laboratory)14 Mar 2025Preprint

Cartilage thickness

upin rats1

1 study

  1. Small chemical molecules increase cartilage thickness in rats.

    “SCM administration led to significant improvements in joint tissue integrity, including increased cartilage thickness”

    Animalschemically induced OAcocktailcartilagefemales

    Experimental Confirmation of Osteoarthritis Repair In Vivo Using Epigenetic Reprogramming with Small Chemical Molecules

    bioRxiv (Cold Spring Harbor Laboratory)14 Mar 2025Preprint

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