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Sip@wm

Sip@wm has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Oct 25, 2026: “Targeted RNA-carrying particles reduced bone loss in mice”.

Intervention

1 paper studies it4 findingsUpdated

1 new paper in 30 daysSee all 1

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Hainan Provincial Department of Science and Technology and 4 more
  • Animals1

What did studies of Sip@wm find?

4

Studies of Sip@wm measured 4 outcomes; the most studied are osteoclast differentiation (1 study), inflammation (1) and bone mechanical strength (1).

Osteoclast differentiation

downin mice1

1 study

  1. Sip@wm inhibits osteoclast differentiation in mice.

    “Transcriptomic and histological analyses support attenuated AP-1-associated inflammatory signaling, suppressed osteoclast differentiation, and modulated extracellular matrix remodeling.”

    Animalsovariectomized micebone

    Targeted RNA-carrying particles reduced bone loss in mice

    Bioactive materials

Inflammation

downin mice1

1 study

  1. Sip@wm decreases inflammation in mice.

    “Transcriptomic and histological analyses support attenuated AP-1-associated inflammatory signaling”

    Animalsovariectomized micebone

    Targeted RNA-carrying particles reduced bone loss in mice

    Bioactive materials

More on Inflammation

Bone mechanical strength

upin mice1

1 study

  1. Sip@wm improves bone mechanical strength in mice.

    “systemic administration of siP@WM ameliorates bone loss, restores trabecular microarchitecture and mechanical strength”

    Animalsovariectomized micebone

    Targeted RNA-carrying particles reduced bone loss in mice

    Bioactive materials

Bone loss

downin mice1

1 study

  1. Sip@wm decreases bone loss in mice.

    “In ovariectomized mice, systemic administration of siP@WM ameliorates bone loss”

    Animalsovariectomized micebone

    Targeted RNA-carrying particles reduced bone loss in mice

    Bioactive materials

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 paper in 12 months
Bioactive Materials

Targeted RNA-carrying particles reduced bone loss in mice

In an experiment in mice with ovaries removed, targeted particles restored spongy bone structure and bone strength.In an experiment in mice with ovaries removed, targeted particles restored spongy bone structure and bone strength.

Mouse studyBones and joints
Paper

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