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SARS-COV-2 omicron variant

Exposure

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Bundesministerium für Bildung und Forschung and 4 more
  • Cells1

Outcomes

2

Senescence-associated secretory phenotype (SASP)

upin human cells1

1 study

  1. SARS-COV-2 omicron variant activates senescence-associated secretory phenotype (SASP) in human cells.

    “Additionally, an upregulated senescence-associated secretory phenotype (SASP) was detected.”

    Cellsin human primary lung cells

    Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence

    AgingDec 12, 2023

More on Senescence-associated secretory phenotype (SASP)

Cellular senescence

upin human cells1

1 study

  1. SARS-COV-2 omicron variant induces cellular senescence in human cells.

    “Solely omicron variants of SARS-CoV-2 influenced the expression of cell cycle genes, highlighted by an increased p21 expression in human primary lung cells and human ex vivo lungs.”

    Cellsin human primary lung cells and human ex vivo lungs

    Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence

    AgingDec 12, 2023

More on Cellular senescence

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