Ruminococcus gnavus

Ruminococcus gnavus has been studied in 4 papers since 2025: 2 observational studies in people, 2 in animals; 2 in the past year. The newest story, Nov 10, 2026: “Gut bacterial product changes blood fat levels in mice”.

Exposure

4 papers study it8 findingsUpdated Nov 10, 2026

1 new paper in 30 daysSee all 4 papers on ruminococcus gnavus

At a glance

The findings reach people, from one lab or study. 4 independent labs in 4 countries.

“We observed a higher prevalence of a Ruminococcus gnavus clade in nonagenarians correlated with distinct plasma bile acid profiles”

Global genetic diversity of human gut microbiome species is related to geographic location and host healthCell2025doi:10.1016/j.cell.2025.04.014

None of its findings points the other way.

4 independent labs in 4 countries

Funders: Basic and Applied Basic Research Foundation of Guangdong Province and others
1 of 8 findings with company ties

Humans2
Animals2

What did studies of ruminococcus gnavus find?

Studies of ruminococcus gnavus measured 3 outcomes: hepatic steatosis, autophagy and cognitive function.

Hepatic steatosis

upin mice1

1 study

Ruminococcus gnavus induces hepatic steatosis in mice (mice fed a normal or high-fat diet).
“Administering R. gnavus to mice fed a normal or high-fat diet induced alterations in circulating lipids and liver function markers, accompanied by hepatic steatosis.”
Animalsmice fed a normal or high-fat dietliver
Gut bacterial product changes blood fat levels in mice
Gut microbesNov 10, 2026

What is ruminococcus gnavus linked with?

Studies link ruminococcus gnavus with 5 measures, among them circulating lipid, major adverse cardiovascular events and cognitive function.

Circulating lipid

mixedin mice1

1 study

Ruminococcus gnavus is associated with circulating lipid in mice (mice fed a normal or high-fat diet).
“Administering R. gnavus to mice fed a normal or high-fat diet induced alterations in circulating lipids and liver function markers”
Animalsmice fed a normal or high-fat diet
Gut bacterial product changes blood fat levels in mice
Gut microbesNov 10, 2026

Latest

2 papers in 12 months

Gut MicrobesNov 10

Gut bacterial product changes blood fat levels in mice

Mice given a bile acid made by the gut bacterium Ruminococcus gnavus developed blood fat disturbances.Mice given a bile acid made by the gut bacterium Ruminococcus gnavus developed blood fat disturbances.

Mouse studyMechanisms