Resolvin D1

2 papers1 finding

1 lab in 1 country

Funder: Agencia Nacional de Investigación y Desarrollo

Cells1

Outcomes

1

Pro-inflammatory SASP mediators

downin rat cells1

1 study

Resolvin D1 decreases pro-inflammatory SASP mediators in rat cells.
“RvD1 treatment significantly reshaped the SASP of senescent CF, reducing pro-inflammatory mediators including IL-1β, IL-6, TNF-α, and MCP-1, while preserving anti-inflammatory cytokines.”
CellsLPS-induced senescencecardiac fibroblast48 h
Resolvin D1 attenuates senescence-associated secretory phenotype independently of TGF-β-driven cardiac fibroblasts differentiation to myofibroblast
Journal of inflammation (London, England)29 Apr 2026

More on Pro-inflammatory SASP mediators

Funding

1 grant since 2025

Agencia Nacional de Investigación y DesarrolloCLP 238k

A NEW CHALLENGE FOR THE RESOLVIN D1: TO RESTORE IMPAIRED MITOCHONDRIAL QUALITY CONTROL SYSTEMS TO HALT CARDIAC FIBROBLAST SENESCENCE AND CARDIAC FIBROSIS TRIGGERED BY ANG II
Agencia Nacional de Investigación y DesarrolloUniversity of ChileCLP 238k2025–2029

Latest

2 in 12 months

Biochemical Pharmacology22 Aug

Immunopharmacological reprogramming of innate immune memory in Alzheimer's disease: From microglial priming to therapeutic resilience

ReviewAlzheimer's disease

Journal of Inflammation30 Apr

Resolvin D1 attenuates senescence-associated secretory phenotype independently of TGF-β-driven cardiac fibroblasts differentiation to myofibroblast

Experiments in rat cellsInterventions

Prostaglandins, Leukotrienes, and Essential Fatty Acids21 Aug

Resolvin D1 suppresses macrophage senescence and splenic fibrosis in aged mice

Experiments in animalsInterventions

Molecular Metabolism16 Nov

Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failure

Experiments in miceInflammation