Renin-angiotensin system inhibition
1 paper4 findings
- 1 lab in 1 country
- Animals1
Outcomes
4Glomerular area
downin rats1
1 study
Glomerular area
downin rats1
Renin-angiotensin system inhibition decreases glomerular area in rats.
“Glomerular area showed significant increase with normal aging and all treatment strategies protected against it.”
Animalsnormal aging
Changes seen in the aging kidney and the effect of blocking the renin-angiotensin system
Therapeutic advances in cardiovascular disease2 Jul 2009
Serum creatinine
downin rats1
1 study
Serum creatinine
downin rats1
Renin-angiotensin system inhibition decreases serum creatinine in rats.
“Proteinuria and serum creatinine increased with age but were reduced in treated animals.”
Animalsnormal aging
Changes seen in the aging kidney and the effect of blocking the renin-angiotensin system
Therapeutic advances in cardiovascular disease2 Jul 2009
Proteinuria
downin rats1
1 study
Proteinuria
downin rats1
Renin-angiotensin system inhibition decreases proteinuria in rats.
“Proteinuria and serum creatinine increased with age but were reduced in treated animals.”
Animalsnormal aging
Changes seen in the aging kidney and the effect of blocking the renin-angiotensin system
Therapeutic advances in cardiovascular disease2 Jul 2009
Glomerular fibrotic changes
downin rats1
1 study
Glomerular fibrotic changes
downin rats1
Renin-angiotensin system inhibition decreases glomerular fibrotic changes in rats (reduced by half).
“Main glomerular changes present in 18-month-old rats were reduced by half in treated animals.”
Animalsnormal aging
Changes seen in the aging kidney and the effect of blocking the renin-angiotensin system
Therapeutic advances in cardiovascular disease2 Jul 2009