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Recombinant progranulin

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Fujian Medical University and 1 more
  • Animals1

Outcomes

1

Osteogenic induction potential

upin mouse cells1

1 study

  1. Recombinant progranulin improves osteogenic induction potential in mouse cells.

    “Treatment with recombinant PGRN (rPGRN) effectively reinstated the osteogenic induction potential of aging Tregs”

    Cellsco-cultured with MC3T3-E1

    Aging impairs the Treg-related osteogenic induction process via the PGRN/EGFR/PI3K/AKT axis

    International journal of biological macromolecules11 Oct 2025

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