Recombinant humanized collagen type iii
1 paper4 findings
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 1 more
- Humans1
Outcomes
3Angiogenesis
upin human cells1upin rats1
1 study
Angiogenesis
upin human cells1upin rats1
Recombinant humanized collagen type iii improves angiogenesis in human cells.
“Furthermore, rhCol III improved the proliferation, migration, and tubule formation capacities of HUVECs.”
CellsHUVECs in vitro
International urogynecology journal21 Mar 2025
Recombinant humanized collagen type iii increases angiogenesis in rats.
“with a marked increase in the levels of CD31, CD34, and VEGFA.”
Animalssimulated birth injury (SBI) modelvaginal wall
International urogynecology journal21 Mar 2025
COL1A1
upin rats1
1 study
COL1A1
upin rats1
Recombinant humanized collagen type iii increases COL1A1 in rats.
“In the vaginal wall, the expression of COL1A1 and COL3A1 in the rhCol group was significantly higher than that in the SBI group”
Animalssimulated birth injury (SBI) modelvaginal wall
International urogynecology journal21 Mar 2025
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Recombinant humanized collagen type iii decreases cellular senescence in human cells.
“At a 1 mg/ml concentration, rhCol III promoted fibroblast proliferation and migration, reduced cellular senescence, and enhanced ECM synthesis.”
CellsPOP patient-derived vaginal fibroblasts1 mg/ml
International urogynecology journal21 Mar 2025