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RB-MOTIF-2

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Chinese University of Hong Kong
  • Animals1

Outcomes

1

Muscle regenerative capacity

upin mice1

1 study

  1. RB-MOTIF-2 improves muscle regenerative capacity in mice.

    “Exogenous RbAp46/48 binding motif (Rb-motif-2) treatment in skeletal muscle could compete for the lncRNA-3 binding, and therefore, enhance the muscle regenerative capacity in the aged mice.”

    Animalsskeletal muscle

    Long Noncoding RNA lncRNA-3 Recruits PRC2 for MyoD1 Silencing to Suppress Muscle Regeneration During Aging

    International journal of molecular sciences20 Nov 2024

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