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LNCRNA-3

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Chinese University of Hong Kong
  • Animals1

Effects

2

Myod1 silencing

upin mice1

1 study

  1. LNCRNA-3 increases myod1 silencing in mice.

    “LncRNA-3 could recruit PRC2 to the MyoD1 promoter and enhance the MyoD1 silencing”

    AnimalsPRC2 recruitment to the MyoD1 promoterskeletal muscle

    Long Noncoding RNA lncRNA-3 Recruits PRC2 for MyoD1 Silencing to Suppress Muscle Regeneration During Aging

    International journal of molecular sciences20 Nov 2024

Muscle regenerative capacity

downin mice1

1 study

  1. LNCRNA-3 impairs muscle regenerative capacity in mice.

    “Muscle-specific lncRNA-3 knockdown could restore the muscle regenerative capacity in the aged mice.”

    Animalsshown by muscle-specific lncRNA-3 knockdownskeletal muscle

    Long Noncoding RNA lncRNA-3 Recruits PRC2 for MyoD1 Silencing to Suppress Muscle Regeneration During Aging

    International journal of molecular sciences20 Nov 2024

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