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PYR-APELIN-13

PYR-APELIN-13 has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Oct 30, 2026: “Daily drug patches improved grip strength in aged mice”.

Intervention

1 paper studies it3 findingsUpdated

PubChemChEBI

See all 1

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab
  • 3 of 3 findings with company ties
  • Animals1

What did studies of PYR-APELIN-13 find?

3

Studies of PYR-APELIN-13 measured 3 outcomes; the most studied are mitochondrial DNA (1 study), grip strength (1) and muscle fiber cross-sectional area (1).

Mitochondrial DNA

upin mice1

1 study

  1. PYR-APELIN-13 increases mitochondrial DNA in aged mice.

    “mitochondrial DNA content increased concordantly”

    Animalsin aged mice

    Daily drug patches improved grip strength in aged mice

    Scientific reports

More on Mitochondrial DNA

Grip strength

upin mice1

1 study

  1. PYR-APELIN-13 improves grip strength in aged mice.

    “Daily MN dosing significantly improved muscle fiber cross-sectional area and grip strength relative to controls”

    Animalsin aged mice

    Daily drug patches improved grip strength in aged mice

    Scientific reports

Muscle fiber cross-sectional area

upin mice1

1 study

  1. PYR-APELIN-13 increases muscle fiber cross-sectional area in aged mice.

    “Daily MN dosing significantly improved muscle fiber cross-sectional area and grip strength relative to controls”

    Animalsin aged mice

    Daily drug patches improved grip strength in aged mice

    Scientific reports

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 paper in 12 months
Scientific Reports

Daily drug patches improved grip strength in aged mice

In a 20-day experiment, daily microneedle patches increased grip strength and muscle fiber size compared with untreated aged mice.In a 20-day experiment, daily microneedle patches increased grip strength and muscle fiber size compared with untreated aged mice.

Mouse studyInterventions
Paper

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