Platinum chemotherapy
Intervention1 paper2 findings
- Humans1
Outcomes
2Mutational signature
upin humans1Low certainty
1 study
Mutational signature
upin humans1Low certainty
Platinum chemotherapy induces mutational signature in humans.
Humansin normal tissues of childrenliver
Extensive and differential platinum chemotherapy mutagenesis in livers of children · Science (New York, N.Y.) · 10 Sep 2026
Somatic mutation burden
upin humans1Low certainty
1 study
Somatic mutation burden
upin humans1Low certainty
Platinum chemotherapy increases somatic mutation burden in humans.
Humansin normal pediatric tissues
Extensive and differential platinum chemotherapy mutagenesis in livers of children · Science (New York, N.Y.) · 10 Sep 2026