Carboplatin
Intervention1 paper1 findingPubChem 426756
- Humans1
Outcomes
1Clonal hematopoiesis of indeterminate potential
upin humans1Very low certainty
1 study
Clonal hematopoiesis of indeterminate potential
upin humans1Very low certainty
Carboplatin increases clonal hematopoiesis of indeterminate potential in humans.
Humanswhole-blood
Germline HRD limits therapy-driven clonal hematopoiesis · Nature genetics · 28 Sep 2026
Latest
1Nature GeneticsHumans
Germline HRD limits therapy-driven clonal hematopoiesis
Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency…Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency reduces this growth.