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Physical and cognitive training

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Consiglio Nazionale delle Ricerche and 3 more
  • Human trial1

Outcomes

3

Cognitive function

upin humans1

1 study

  1. Physical and cognitive training improves cognitive function in humans.

    “The TTB intervention not only improved cognitive and physical outcomes but also modulated key immune markers associated with neuroinflammation and aging.”

    Human trialMild Cognitive Impairmentn = 76

    An inflammatory fingerprint in mild cognitively impaired patients is reversed by physical and cognitive training

    Brain, behavior, & immunity - health18 Jul 2025

IL-17A

downin humans1

1 study

  1. Physical and cognitive training decreases IL-17A in humans.

    “Following the TTB intervention, we observed reductions in IL-6, IL-17A, TNFα, and CCL11 levels.”

    Human trialMild Cognitive Impairmentplasman = 76

    An inflammatory fingerprint in mild cognitively impaired patients is reversed by physical and cognitive training

    Brain, behavior, & immunity - health18 Jul 2025

More on IL-17A

IL-6

downin humans1

1 study

  1. Physical and cognitive training decreases IL-6 in humans.

    “Following the TTB intervention, we observed reductions in IL-6, IL-17A, TNFα, and CCL11 levels.”

    Human trialMild Cognitive Impairmentplasman = 76

    An inflammatory fingerprint in mild cognitively impaired patients is reversed by physical and cognitive training

    Brain, behavior, & immunity - health18 Jul 2025

More on IL-6

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