Social participation + physical activity

1. Social participation + physical activity lowers the risk of motoric cognitive risk syndrome in humans (RR 0.78, 95% CI 0.58–0.99).

   “The joint scenario targeting social participation and physical activity also yielded a lower estimated risk (risk ratio 0.78, 95% confidence interval 0.58-0.99).”

   HumansParametric g-formula estimate versus the natural course; not an implemented interventionjoint hypothetical intervention4 yearsn = 2,299

   Multi-domain interventions for the prevention of motoric cognitive risk syndrome among Chinese older adults: An application of the parametric G-formula based on an intrinsic capacity framework

   Maturitas·7 Oct 2026

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