Photic deprivation

Photic deprivation has been studied in 1 paper since 2018: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Sep 27, 2018: “Photo-regulation of rod precursor cell proliferation”.

Exposure

1 paper studies it3 findingsUpdated

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: National Eye Institute and 2 more
  • Animals1

What did studies of Photic deprivation find?

3

Studies of Photic deprivation measured 3 outcomes; the most studied are rod precursor cell differentiation into rod photoreceptors (1 study), Müller glia and neuronal progenitor cell proliferation (1) and rod precursor cell proliferation (1).

Rod precursor cell differentiation into rod photoreceptors

no changein zebrafish1

1 study
  1. Photic deprivation has no effect on rod precursor cell differentiation into rod photoreceptors in zebrafish.

    “differentiated into rod photoreceptors at a comparable percentage and in a similar time frame as those maintained under standard light conditions”

    Animalscompared with standard light conditionsretina

    Photo-regulation of rod precursor cell proliferation

    Experimental eye research

Müller glia and neuronal progenitor cell proliferation

no changein zebrafish1

1 study
  1. Photic deprivation has no effect on Müller glia and neuronal progenitor cell proliferation in zebrafish.

    “the number of proliferating Müller glia and their derived olig2:EGFP-positive neuronal progenitor cells was not significantly changed.”

    Animalsretina

    Photo-regulation of rod precursor cell proliferation

    Experimental eye research

Rod precursor cell proliferation

upin zebrafish1

1 study
  1. Photic deprivation increases rod precursor cell proliferation in zebrafish.

    “In dark-adapted retinas, rod precursor cell proliferation increased”

    Animalscompared with standard light conditionsretina

    Photo-regulation of rod precursor cell proliferation

    Experimental eye research

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