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Panax japonicus

Intervention

1 paper studies it5 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Natural Science Foundation of Yichang City
  • Animals1

Outcomes

5

Autophagy

upin rats1

1 study

  1. Panax japonicus activates autophagy in rats.

    “SPJ activated autophagy through the activation of AMPK, which in turn increased the phosphorylation of ULK1(Ser555), while inhibited the phosphorylation of mTOR and ULK1(Ser757).”

    Animalsnatural aging

    Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway

    Experimental gerontologyOct 6, 2023

More on Autophagy

Apoptosis

downin rats1

1 study

  1. Panax japonicus decreases apoptosis in rats.

    “decreased collagen deposition and cardiomyocyte apoptosis in aging rats.”

    Animalsnatural aging

    Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway

    Experimental gerontologyOct 6, 2023

More on Apoptosis

Fibrosis

downin rats1

1 study

  1. Panax japonicus decreases fibrosis in rats.

    “decreased collagen deposition and cardiomyocyte apoptosis in aging rats.”

    Animalsnatural aging

    Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway

    Experimental gerontologyOct 6, 2023

Heart mass index

downin rats1

1 study

  1. Panax japonicus decreases heart mass index in rats.

    “SPJ treatment improved the cardiac function, reduced HMI, attenuated myocardial fiber disorder, inhibited inflammatory cell infiltration, and decreased collagen deposition and cardiomyocyte apoptosis in aging rats.”

    Animalsnatural aging

    Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway

    Experimental gerontologyOct 6, 2023

More on Heart mass index

Cardiac function

upin rats1

1 study

  1. Panax japonicus improves cardiac function in rats.

    “SPJ treatment improved the cardiac function, reduced HMI, attenuated myocardial fiber disorder, inhibited inflammatory cell infiltration, and decreased collagen deposition and cardiomyocyte apoptosis in aging rats.”

    Animalsnatural aging

    Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway

    Experimental gerontologyOct 6, 2023

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