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Oskm-mediated reprogramming

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab
  • Humans1

Outcomes

1

IntrinClock

downin human cells1

1 study

  1. Oskm-mediated reprogramming decreases IntrinClock in human cells.

    “IntrinClock showed a robust predicted epigenetic age increase in a model of replicative senescence in vitro and age reversal during OSKM-mediated reprogramming.”

    Cells

    Development of a novel epigenetic clock resistant to changes in immune cell composition

    bioRxiv (Cold Spring Harbor Laboratory)2 Mar 2023Preprint

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