NUT2

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funder: MEDA Pharma
  • 4 of 4 findings with company ties
  • Human trial1

Outcomes

3

Homocysteine

downin humans1

1 study
  1. NUT2 decreases homocysteine in humans.

    “Significant reductions in homocysteine and lower fasting insulin concentrations were observed with NUT2.”

    Human trial12 weeks

    Effects of a Multi-Component Nutraceutical (NUT2) on the Lipid Profile in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial

    Nutrients12 Aug 2026

More on Homocysteine

Total cholesterol

downin humans1

1 study
  1. NUT2 decreases total cholesterol in humans (-26 mg/dL (95% CI -36 to -17; p < 0.001)).

    “Total cholesterol was also significantly reduced (corrected difference -26 mg/dL, 95% CI -36 to -17; p < 0.001).”

    Human trial12 weeks

    Effects of a Multi-Component Nutraceutical (NUT2) on the Lipid Profile in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial

    Nutrients12 Aug 2026

More on Total cholesterol

LDL-C

downin humans1

1 study
  1. NUT2 decreases LDL-C in humans (-23 mg/dL (95% CI -29 to -16; p < 0.001)).

    “the baseline-corrected between-group difference was -23 mg/dL (95% CI -29 to -16; p < 0.001)”

    Human trial12 weeks

    Effects of a Multi-Component Nutraceutical (NUT2) on the Lipid Profile in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial

    Nutrients12 Aug 2026

More on LDL-C

Associations

1

Metabolic syndrome

downin humans1

1 study
  1. NUT2 lowers the risk of metabolic syndrome in humans (13.3% vs 37.8% (p = 0.008)).

    “Metabolic syndrome prevalence was 13.3% with NUT2 versus 37.8% with placebo at Week 12 (p = 0.008)”

    Human trial12 weeks

    Effects of a Multi-Component Nutraceutical (NUT2) on the Lipid Profile in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial

    Nutrients12 Aug 2026

More on Metabolic syndrome

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