Non-nicotinized e-cigarettes

1. Non-nicotinized e-cigarettes increase peripheral flow reserve in humans (+32%).

   “PFR (e-cig−: +32%; t-cig: +31%)”

   Human trialpost-challenge across usersfemoral arteryn = 41

   Acute Effects of Smoking and Vaping on Markers of Vascular Function via Quantitative MRI

   Journal of magnetic resonance imaging : JMRI·7 Jul 2026

More on Peripheral flow reserve

1. Non-nicotinized e-cigarettes decrease venous oxygen saturation in humans (-14%).

   “post-challenge, the following decreased significantly: baseline SvO2 (e-cig+: -12%; e-cig−: -14%; t-cig: -9%)”

   Human trialpost-challenge in smokers/vapersfemoral veinn = 41

   Acute Effects of Smoking and Vaping on Markers of Vascular Function via Quantitative MRI

   Journal of magnetic resonance imaging : JMRI·7 Jul 2026

More on Venous oxygen saturation