Nerve guidance conduit

1. Nerve guidance conduit decreases cellular senescence in pigs.

   “mitigating oxidative stress-induced premature senescence of cardiac cells”

   Animalsright cardiac vagotomyheartmales

   Reconnecting the vagus nerve to the heart through nerve conduit preserves cardiac function in a minipig model of right cardiac vagotomy

   Science translational medicine·24 Dec 2025

More on Cellular senescence

1. Nerve guidance conduit prevents interstitial fibrosis in pigs.

   “prevention of interstitial fibrosis”

   Animalsright cardiac vagotomymyocardiummales

   Reconnecting the vagus nerve to the heart through nerve conduit preserves cardiac function in a minipig model of right cardiac vagotomy

   Science translational medicine·24 Dec 2025

1. Nerve guidance conduit improves cardiac mechanical function in pigs.

   “early reconnection of the right vagus nerve using an implantable chitosan/poly-ε-caprolactone cuff-like nerve guidance conduit preserved cardiac mechanical function”

   Animalsright cardiac vagotomyheartmales

   Reconnecting the vagus nerve to the heart through nerve conduit preserves cardiac function in a minipig model of right cardiac vagotomy

   Science translational medicine·24 Dec 2025