Nasturtium officinale

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Chiang Mai University and 2 more

Human trial1

Outcomes

Glycine

upin humans1

1 study

Nasturtium officinale increases glycine in humans.
“while increasing glycine and dimethylglycine”
Human triallow-to-moderate cardiovascular riskdried watercress capsules8 g/day28 daysn = 26
Untargeted ¹H-NMR Metabolomics Identifies Candidate Metabolic Changes Associated with Watercress (Nasturtium officinale R.Br.) Supplementation in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial
Nutrients5 Aug 2026

More on Glycine

Tryptophan–kynurenine metabolism

downin humans1

1 study

Nasturtium officinale decreases tryptophan–kynurenine metabolism in humans.
“Watercress supplementation reduced metabolites associated with oxidative DNA damage, inflammatory kynurenine metabolism”
Human triallow-to-moderate cardiovascular riskdried watercress capsules8 g/day28 daysn = 26
Untargeted ¹H-NMR Metabolomics Identifies Candidate Metabolic Changes Associated with Watercress (Nasturtium officinale R.Br.) Supplementation in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial
Nutrients5 Aug 2026

More on Tryptophan–kynurenine metabolism

Oxidative stress and ROS signalling

downin humans1

1 study

Nasturtium officinale decreases oxidative stress and ROS signalling in humans.
“Watercress supplementation reduced metabolites associated with oxidative DNA damage”
Human triallow-to-moderate cardiovascular riskdried watercress capsules8 g/day28 daysn = 26
Untargeted ¹H-NMR Metabolomics Identifies Candidate Metabolic Changes Associated with Watercress (Nasturtium officinale R.Br.) Supplementation in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial
Nutrients5 Aug 2026

More on Oxidative stress and ROS signalling

LDL cholesterol

downin humans1

1 study

Nasturtium officinale decreases LDL cholesterol in humans.
“Conventional biomarkers showed a significant decrease in low-density lipoprotein cholesterol”
Human triallow-to-moderate cardiovascular riskdried watercress capsules8 g/day28 daysn = 26
Untargeted ¹H-NMR Metabolomics Identifies Candidate Metabolic Changes Associated with Watercress (Nasturtium officinale R.Br.) Supplementation in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial
Nutrients5 Aug 2026

Latest

1 in 12 months

Nutrients13 Aug

Untargeted ¹H-NMR Metabolomics Identifies Candidate Metabolic Changes Associated with Watercress (Nasturtium officinale R.Br.) Supplementation in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial

Randomised trial in 26 peopleInterventions

Paper

Nasturtium officinale

Outcomes

Latest

Untargeted ¹H-NMR Metabolomics Identifies Candidate Metabolic Changes Associated with Watercress (Nasturtium officinale R.Br.) Supplementation in Adults with Low-to-Moderate Cardiovascular Risk: A Randomized Placebo-Controlled Trial

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