Multicomponent exercise + nutritional intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab

Outcomes

Depressive symptoms

downin humans1

1 study

Multicomponent exercise + nutritional intervention decreases depressive symptoms in humans (Hedges' g = -0.51, 95% CI -0.93–-0.09).
“and depressive symptoms ( g = -0.51, 95% CI: -0.93~-0.09) in older adults”
ReviewUnadjusted pooled estimate; publication-bias-adjusted confidence interval crossed zero
Effects of multicomponent exercise combined with nutritional intervention on global cognitive function and depressive symptoms in older adults: a systematic review and meta-analysis
BMC geriatrics13 Oct 2026

Latest

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BMC Geriatrics5 h

Effects of multicomponent exercise combined with nutritional intervention on global cognitive function and depressive symptoms in older adults: a systematic review and meta-analysis

Meta-analysis of randomised trialsMulticomponent exercise

Paper

Multicomponent exercise + nutritional intervention

Outcomes

Latest

Effects of multicomponent exercise combined with nutritional intervention on global cognitive function and depressive symptoms in older adults: a systematic review and meta-analysis

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