Moderate-protein, moderate-high-fat, moderate-low-carbohydrate dietary cluster

1. Moderate-protein, moderate-high-fat, moderate-low-carbohydrate dietary cluster is associated with biological-age acceleration in humans (OR 1.25, 95% CI 1.03–1.50; FDR q = 0.086).

   “the Pm: Fmh: Cml cluster (moderate protein, moderate-high fat, moderate-low carbohydrate) (OR: 1.25, 95% CI: 1.03–1.50) showed suggestive positive associations with AA.”

   HumansCompared with the moderate-protein, moderate-fat, moderate-high-carbohydrate cluster; not significant after FDR correctionn = 25,987

   Specific macronutrient clusters associated with biological aging

   Scientific reports·13 Oct 2026

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