Mir-9/9*-124

Mir-9/9*-124 induces pan-neuronal state in humans.

“miR-9/9* and miR-124 (miR-9/9*-124) display neurogenic and cell fate-switching activities when ectopically expressed in human fibroblasts by erasing fibroblast identity and inducing a pan-neuronal state.”

Reviewin human fibroblasts

Patient-derived neuron model: Capturing age-dependent adult-onset degenerative pathology in Huntington's disease

Molecules and cells·16 Mar 2024