MIR-192
1 paper3 findings
- 1 lab in 1 country
- Funders: Japan Agency for Medical Research and Development and 1 more
- Animals1
Outcomes
3JAK–STAT signalling
downin mice1
1 study
JAK–STAT signalling
downin mice1
MIR-192 inhibits JAK–STAT signalling in mice.
“miR-192 inhibited key components of the JAK-STAT signaling pathway, crucial for cytokine receptor signaling in myeloid cells.”
Animalsmyeloid cells
Molecular therapy. Nucleic acids26 Nov 2025
Senescence-associated secretory phenotype (SASP)
downin mice1
1 study
Senescence-associated secretory phenotype (SASP)
downin mice1
MIR-192 inhibits senescence-associated secretory phenotype (SASP) in mice.
“miR-192 downregulated multiple pro-inflammatory cytokines, such as senescence-associated secreted phenotype factors”
Animals
Molecular therapy. Nucleic acids26 Nov 2025
Vaccine efficacy
upin mice1
1 study
Vaccine efficacy
upin mice1
MIR-192 improves vaccine efficacy in mice.
“miR-192 endowed LNPs with strong anti-inflammatory properties, markedly enhancing vaccine efficacy, especially in aged mice.”
Animalsin aged mice
Molecular therapy. Nucleic acids26 Nov 2025
Latest
1 in 12 monthsMolecular Therapy Nucleic Acids
Lipid nanoparticle-encapsulated microRNA-192: An anti-inflammatory adjuvant that enhances vaccine efficacy in aged mice
Experiments in miceInterventions