Microfluidic mechanical compression

Intervention

1 paper4 findings

Microfluidic mechanical compression reduces senescence-associated beta-galactosidase and SASP and increases POU5F1 in late-passage stem cells; a mouse study reports improved tissue repair with these cells. All four findings come from one lab in one country, with Samsung, the Ministry of Science and ICT, and National Research Foundation bodies named as funders.

  • 1 lab in 1 country
  • Funders: Ministry of Science and ICT, South Korea and 3 more
  • Cells1

Outcomes

4

Tissue repair

upin animals1

1 study
  1. Microfluidic mechanical compression improves tissue repair.

    Animalswith late-passage stem cells

    Microfluidic Mechanical Reactivation of Senescent Stem Cells

    Small (Weinheim an der Bergstrasse, Germany)9 Sep 2026

Senescence-associated secretory phenotype (SASP)

downin cells1

1 study
  1. Microfluidic mechanical compression inhibits senescence-associated secretory phenotype (SASP) in cells.

    Cellsin late-passage stem cells

    Microfluidic Mechanical Reactivation of Senescent Stem Cells

    Small (Weinheim an der Bergstrasse, Germany)9 Sep 2026

More on Senescence-associated secretory phenotype (SASP)

POU5F1

upin cells1

1 study
  1. Microfluidic mechanical compression increases POU5F1 in cells.

    Cellsin late-passage stem cells

    Microfluidic Mechanical Reactivation of Senescent Stem Cells

    Small (Weinheim an der Bergstrasse, Germany)9 Sep 2026

More on POU5F1

Senescence-associated beta-galactosidase

downin cells1

1 study
  1. Microfluidic mechanical compression decreases senescence-associated beta-galactosidase in cells.

    Cellsin late-passage stem cells

    Microfluidic Mechanical Reactivation of Senescent Stem Cells

    Small (Weinheim an der Bergstrasse, Germany)9 Sep 2026

More on Senescence-associated beta-galactosidase

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