MC1

MC1 has been studied in 2 papers since 2023: 1 observational study in people, 1 in animals; 1 in the past year. The newest paper, Jul 5, 2026: “A Melatonin-Catechol Hybrid Molecule Prolongs Lifespan via Regulating ROS and Reprogramming Mitochondrial Metabolism”.

Intervention

2 papers study it3 findingsUpdated

See all 2

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: Ministry of Education of China and 1 more
  • Humans1
  • Model organisms1

What did studies of MC1 find?

3

Studies of MC1 measured 3 outcomes; the most studied are muscle strength (1 study), lifespan (1) and cellular senescence (1).

Muscle strength

upin worms1

1 study
  1. MC1 improves muscle strength in worms.

    “accompanied by an improvement in muscle strength and physiological functions”

    Model organisms

    A Melatonin-Catechol Hybrid Molecule Prolongs Lifespan via Regulating ROS and Reprogramming Mitochondrial Metabolism

    Journal of medicinal chemistry

Lifespan

upin worms1

1 study
  1. MC1 extends lifespan in worms.

    “MC1 significantly extends the lifespan of Caenorhabditis elegans”

    Model organisms

    A Melatonin-Catechol Hybrid Molecule Prolongs Lifespan via Regulating ROS and Reprogramming Mitochondrial Metabolism

    Journal of medicinal chemistry

Cellular senescence

downin worms1

1 study
  1. MC1 inhibits cellular senescence in worms.

    “MC1 combats cell senescence under oxidative stress and DNA damage”

    Model organismsunder oxidative stress and DNA damage

    A Melatonin-Catechol Hybrid Molecule Prolongs Lifespan via Regulating ROS and Reprogramming Mitochondrial Metabolism

    Journal of medicinal chemistry

More on Cellular senescence

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 0Oct 2026: 01 paper in 12 months