Maize

2 papers2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

2 independent labs in 2 countries

Funders: China Agricultural Research System and 5 more

Humans1
Model organisms1

Outcomes

Juvenile hormone III

downin M. hieroglyphica1

1 study

Maize decreases juvenile hormone III in M. hieroglyphica (p < 0.0001).
“Titration revealed significantly decreased JHIII but increased CoQ9 and CoQ10 levels in maize-fed versus soybean-fed beetles at day 11 (p < 0.0001).”
Model organismsmaize-fed versus soybean-fed
Decaprenyl diphosphate synthases in Monolepta hieroglyphica: DPPS-mediated CoQ biosynthesis impacts juvenile hormone and gut microbiota
Insect biochemistry and molecular biology30 Oct 2025

Associations

Dementia

downin humans1

1 study

Maize is associated with dementia in humans.
“Wheat consumption was positively associated with dementia incidence, affluence, and longevity, whereas rice and maize consumption showed inverse associations.”
Humans
Ageing, Wealth, and Diet: A Global Cross-National Analysis of Cereal Consumption and Dementia Risk
Dementia and geriatric cognitive disorders2 Mar 2026