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Macrophage-derived extracellular vesicles

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 4 more
  • Cells1

Outcomes

2

Antibacterial defenses

downin cells1

1 study

  1. Macrophage-derived extracellular vesicles impair antibacterial defenses in cells.

    “promote cellular senescence, and compromise antibacterial defenses upon internalization.”

    Cellsupon internalization of MφV-EVs

    TREM-1-Linked Inflammatory Cargo in SARS-CoV-2-Stimulated Macrophage Extracellular Vesicles Drives Cellular Senescence and Impairs Antibacterial Defense

    Viruses24 Apr 2025

Cellular senescence

upin cells1

1 study

  1. Macrophage-derived extracellular vesicles induce cellular senescence in cells.

    “These EVs carry senescence-associated secretory phenotype (SASP) components, promote cellular senescence, and compromise antibacterial defenses upon internalization.”

    Cellsupon internalization of MφV-EVs

    TREM-1-Linked Inflammatory Cargo in SARS-CoV-2-Stimulated Macrophage Extracellular Vesicles Drives Cellular Senescence and Impairs Antibacterial Defense

    Viruses24 Apr 2025

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